CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
673 results for "CTLA-4" in Products
673 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Antitope patent anti-CTLA4 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6868R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6864R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #CTLA4/6867R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Antitope patent anti-CTLA4 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #rCTLA4/7219 |
Applications: | IHC |
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
Applications: | Simple Plex |
Source: | Sf 21 (baculovirus) |
Accession #: | Q6GR94 |
Applications: | BA |
Source: | CHO |
Accession #: | P16410 |
Applications: | BA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Flow, CyTOF-ready, ICC |
Simple Plex Human CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Source: | NS0 |
Accession #: | Q6GTR6 |
Applications: | BA |
Sensitivity: | 0.13 pg/mL |
Applications: | ELISA |
Assay Range: | 0.781 - 50 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 Monoclonal Clone #1003705 |
Applications: | WB, AgAct |
Biotinylated
Source: | HEK293 |
Accession #: | P16410.3 |
Applications: | BA |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Source: | HEK293 |
Accession #: | XP_005574071 |
Applications: | BA |
Assay Range: | 125 - 8,000 pg/mL |
Applications: | ELISA |
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
Simple Plex Non-Human Primate CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.