Human ER beta/NR3A2 Antibody

R&D Systems, part of Bio-Techne | Catalog # PP-PPZ0506-00

R&D Systems, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse, Transgenic Mouse

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # PPZ0506

View all ER beta/NR3A2 Antibodies »

Product Specifications

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human ER beta/NR3A2 Antibody

Application
Recommended Usage

Immunoprecipitation

Western Blot

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using PP-PPZ0506-00 in the following applications:

Formulation, Preparation, and Storage

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ER beta/NR3A2

Estrogen Receptor beta (ERβ,NR3A2) is a member of the steroid receptor family. The natural ligand for ER is the classical estrogenic compound 17β-estradiol. ERβ is expressed in the granulosa cell layer of primary, secondary and mature follicles in the ovary, in bone, bladder, uterus, testis, epididymis, gastrointestinal tract, kidney, breast, heart, vessel wall, immune system, lung, pituitary, hippocampus and hypothalamus. Roles for ERβ in the reproductive and cardiovascular systems have been reported, although these are the subject of conflicting reports. ERβ has been postulated to act primarily as a modulator of ERα function. ER&beta has been shown to form homodimers as well as heterodimers with ERα. Both ERα and ERβ can give rise to numerous isoforms.

Long Name

Estrogen Receptor beta

Alternate Names

ESR2, NR3A2

Entrez Gene IDs

2100 (Human)

Gene Symbol

ESR2

Additional ER beta/NR3A2 Products

Product Documents for Human ER beta/NR3A2 Antibody

Product Datasheets

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human ER beta/NR3A2 Antibody

For research use only

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