Human GluR7/GRIK3 Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB11328
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 1059901
Product Specifications
Immunogen
Human GluR7/GRIK3 containing peptide.
Accession # Q13003
Accession # Q13003
Specificity
Detects human GluR7/GRIK3 in direct ELISA.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Scientific Data Images for Human GluR7/GRIK3 Antibody
Detection of GluR7/GRIK3 in Human Hippocampus.
GluR7/GRIK3 was detected in immersion fixed paraffin-embedded sections of Human Hippocampus using Mouse Anti-Human GluR7/GRIK3 Monoclonal Antibody (Catalog # MAB11328) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in neuronal cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.Applications for Human GluR7/GRIK3 Antibody
Application
Recommended Usage
Immunohistochemistry
5-25 µg/mL
Sample: Immersion fixed paraffin-embedded sections of Human Hippocampus
Sample: Immersion fixed paraffin-embedded sections of Human Hippocampus
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: GluR7/GRIK3
References
- Entrez Gene: GRIK3 glutamate receptor, ionotropic, kainate 3.
- Matute C. "Therapeutic Potential of Kainate Receptors". CNS Neuroscience & Therapeutics. 2011 Dec; 17(6):661.
- Begni S, Popoli M, Moraschi S, Bignotti S, Tura G.B, Gennarelli M., "Association Between the Ionotropic Glutamate Receptor Kainate 3 (GRI3) Ser310Ala Polymorphism and Schizophrenia". Mol Psychiatry. 2002; 7(4):416.
Long Name
Glutamate Receptor 7
Alternate Names
EAA5, GLR7, GluK3, GRIK3
Gene Symbol
GRIK3
UniProt
Additional GluR7/GRIK3 Products
Product Documents for Human GluR7/GRIK3 Antibody
Product Specific Notices for Human GluR7/GRIK3 Antibody
For research use only
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