Human peripheral blood mononuclear cells (PBMCs) were stained with (A) Mouse Anti-Human KIR2DS5/CD158g PE-conjugated Monoclonal Antibody (Catalog # FAB8920P) or (B) Rabbit IgG PE-conjugated Isotype Control (Catalog # IC1051P) and Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A). View our protocol for Staining Membrane-associated Proteins.

Detection of KIR2DS5/CD158g in BaF3 Mouse Cell Line Transfected with KIR2DS5/CD158g by Flow Cytometry.

BaF3 mouse pro-B cell line transfected with KIR2DS5/CD158g were stained with Rabbit Anti-Human KIR2DS5/CD158g PE‑conjugated Monoclonal Antibody (Catalog # FAB8920P, filled histogram) or control antibody Rabbit IgG PE‑conjugated Monoclonal Antibody (IC1051P, open histogram). Staining was performed Staining Membrane-associated Proteins protocol.

Applications for Human KIR2DS5/CD158g PE-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: Human PBMC and BaF3 mouse pro-B cell line transfected with KIR2DS5/CD158g

Formulation, Preparation, and Storage

Purification

Protein A or G purified from cell culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: KIR2DS5/CD158g

Killer-immunoglobulin-like receptors (KIR) are polymorphous activating and inhibitory receptors expressed on the surface of NK cells and some T cells. KIR genes are highly homologous. KIR proteins expressing the long (L) cytoplasmic domain are inhibitory, while KIRs with short (S) cytoplasmic domains are activating. Thus, KIR2DS5 is an activating receptor for NK cells, and is thought to play a role in NK cell function in response to a number of conditions. While many KIR proteins bind HLA-class I molecules, the ligand(s) for KIR2DS5 remain unknown.

Long Name

Killer Cell Immunoglobulin-like Receptor, Two Domains, Short Cytoplasmic Tail, 5

Alternate Names

CD158g, NKAT9

Entrez Gene IDs

3810 (Human)

Gene Symbol

KIR2DS5

UniProt

Q14953

Additional KIR2DS5/CD158g Products

Product Documents for Human KIR2DS5/CD158g PE-conjugated Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human KIR2DS5/CD158g PE-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human KIR2DS5/CD158g PE-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB8920P

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all KIR2DS5/CD158g Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human KIR2DS5/CD158g PE-conjugated Antibody

Detection of KIR2DS5/CD158g in Human PBMCs by Flow Cytometry.