Human/Mouse/Primate SLC6A3/DAT1 C-Terminus Antibody
R&D Systems, part of Bio-Techne | Catalog # PPS068
Key Product Details
Species Reactivity
Human, Mouse, Primate
Applications
Immunohistochemistry, Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Product Specifications
Immunogen
SLC6A3/DAT1
Specificity
Specific for the ~88 kDa DAT protein in Western blots of SDS-solubilized human and mouse striatal samples and in IHC applications with formaldehyde-fixed human and monkey (Macaque) brain sections.
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Scientific Data Images for Human/Mouse/Primate SLC6A3/DAT1 C-Terminus Antibody
Detection of SLC6A3/DAT1 (C-Terminus) by Western Blot.
Western blot of human caudate lysate showing specific immunolabeling of the ~88 kDa DAT protein.Applications for Human/Mouse/Primate SLC6A3/DAT1 C-Terminus Antibody
Application
Recommended Usage
Immunohistochemistry
1:1000 dilution
Sample: (frozen sections)
Sample: (frozen sections)
Western Blot
1:1000 dilution
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
100 μL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
For long-term storage, ≤ -20° C is recommended. Product is stable at ≤ -20° C for at least 1 year.
Background: SLC6A3/DAT1
DAT C-terminus. The human EC loop is also 93% aa identical to the rhesus monkey EC loop.
References
- Torres, G.E. (2006) J. Neurochem. 97(Suppl. 1):3.
- Sotnikova, T.D. et al. (2006) CNS Neurol. Disord. Drug Targets. 5:45.
- Fog, J.U. et al. (2006) Neuron 51:417.
- Giros, B. et al. (1992) Mol. Pharmacol. 42:383.
- Cervinski, M.A. et al. (2005) J. Biol. Chem. 280:40442.
Long Name
Dopamine Transporter
Alternate Names
DAT1, SLC6A3, VNTR
Gene Symbol
SLC6A3
Additional SLC6A3/DAT1 Products
Product Documents for Human/Mouse/Primate SLC6A3/DAT1 C-Terminus Antibody
Product Specific Notices for Human/Mouse/Primate SLC6A3/DAT1 C-Terminus Antibody
For research use only
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