Human PILR-beta Biotinylated Antibody
R&D Systems, part of Bio-Techne | Catalog # BAF4189
Key Product Details
Species Reactivity
Human
Applications
Western Blot
Label
Biotin
Antibody Source
Polyclonal Sheep IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human PILR-beta isoform 1
Gln20-Ala189
Accession # Q9UKJ0
Gln20-Ala189
Accession # Q9UKJ0
Specificity
Detects human PILR-beta in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human PILR-alpha is observed and less than 5% cross-reactivity with recombinant mouse PILR-beta, rmPILR-alpha, and rmPILR-L is observed.
Clonality
Polyclonal
Host
Sheep
Isotype
IgG
Applications for Human PILR-beta Biotinylated Antibody
Application
Recommended Usage
Western Blot
0.1 µg/mL
Sample: Recombinant Human PILR-beta
Sample: Recombinant Human PILR-beta
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: PILR-beta
Paired immunoglobulin-like, type 2 receptor beta (PILR-beta) is a type I transmembrane (TM) glycoprotein belonging to the Ig superfamily. It is the activating counterpart to the ITIM-bearing PILR-alpha inhibitory receptor. PILR-beta is expressed in a wide variety of tissues including hematopoietic cells. Mature human PILR-beta is a 208 amino acid (aa) protein with one V-type Ig-like extracellular domain, a truncated cytoplasmic tail, and positively-charged residues in its TM domain that interacts with ITAM‑bearing adaptor molecules. Within the V-type Ig-like region in their ECD, human PILR-beta and PILR-alpha share a 92% aa sequence identity. The aa sequence of mouse PILR-beta ECD is only 43% identical to that of the human protein.
Long Name
Paired-Ig-likeType 2 Receptor beta
Alternate Names
FDFACT1, FDFACT2, PILRB, PILRbeta
Gene Symbol
PILRB
UniProt
Additional PILR-beta Products
Product Documents for Human PILR-beta Biotinylated Antibody
Product Specific Notices for Human PILR-beta Biotinylated Antibody
For research use only
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