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Human PSGR Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB10669

R&D Systems, part of Bio-Techne
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MAB10669-100
MAB10669-SP

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1033009

Product Specifications

Immunogen

Human PSGR synthetic peptide
Accession # Q9H255

Specificity

Detects human PSGR in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human PSGR Antibody

PSGR in Human Prostate.

PSGR was detected in immersion fixed paraffin-embedded sections of human normal prostate using Mouse Anti-Human PSGR Monoclonal Antibody (Catalog # MAB10669) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in glandular epithelial cells. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Applications for Human PSGR Antibody

Application
Recommended Usage

Immunohistochemistry

5-25 µg/mL
Sample: Immersion fixed paraffin-embedded sections of human normal prostate

Reviewed Applications

Read 1 review rated 5 using MAB10669 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Reconstitution Buffer Available:
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Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: PSGR

PSGR (OR51E2) is an olfactory receptor and part of a large family of GPCR's arising from single coding-exon genes.  Odorant receptors represent the largest GPCR family in the human genome and are found to be ectopically expressed in non-sensory tissues mediating a variety of cellular functions.  OR51E2 is well-characterized in prostate cancer and epidermal pigment cells and expressed in the cytosol and in the plasma membrane.  OR51E2 is involved in the regulation of RPE cell growth and is a potential target for the treatment of proliferative disorders.

Long Name

Prostate-Specific G-Protein Coupled Receptor

Alternate Names

HPRAJ, Olfactory Receptor OR11-16, OR51E2, OR51E3P, OR52A2

Entrez Gene IDs

81285 (Human)

Gene Symbol

OR51E2

UniProt

Additional PSGR Products

Product Documents for Human PSGR Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human PSGR Antibody

For research use only

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