HEK293 human embryonic kidney cell line transfected with human SLC19A1 and eGFP were stained with either (A) Mouse Anti-Human Reduced Folate Carrier/SLC19A1 APC-conjugated Monoclonal Antibody (Catalog # FAB8450A) or (B) Mouse IgG_2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Reduced Folate Carrier/SLC19A1 APC-conjugated Antibody

Application

Recommended Usage

Flow Cytometry

10 µL/10⁶ cells
Sample: HEK293 human embryonic kidney cell line transfected with human SLC19A1 and eGFP

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: Reduced Folate Carrier/SLC19A1

SLC19A1, also known as Reduced Folate Carrier protein, is a multi-pass transmembrane transporter that is involved in the regulation of intracellular concentrations of folate. There is an association between idiopathic Recurrent Spontaneous Abortion (RSA) and SLC19A1 polymorphisms that may be useful biomarkers for RSA risk. Three transcript variants encoding different isoforms have been found for this gene. Human and mouse SLC19A1 share only 58% amino acid (aa) sequence identity, with considerable divergence over the C-terminal 100 aa.

Long Name

Solute Carrier Family 12 (Folate Transporter) Member 3

Alternate Names

CHMD, FOLT, IFC1, REFC, RFC1

Entrez Gene IDs

6573 (Human); 20509 (Mouse); 29723 (Rat)

Gene Symbol

SLC19A1

UniProt

P41440

Additional Reduced Folate Carrier/SLC19A1 Products

Product Documents for Human Reduced Folate Carrier/SLC19A1 APC-conjugated Antibody

Product Datasheets

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COA

SDS

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Product Specific Notices for Human Reduced Folate Carrier/SLC19A1 APC-conjugated Antibody

For research use only

Citations
Reviews

Spectra Viewer
Flow Cytometry

Human Reduced Folate Carrier/SLC19A1 APC-conjugated Antibody

R&D Systems, part of Bio-Techne | Catalog # FAB8450A

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all Reduced Folate Carrier/SLC19A1 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human Reduced Folate Carrier/SLC19A1 APC-conjugated Antibody

Detection of Reduced Folate Carrier/SLC19A1 in HEK293 Human Cell Line Transfected with Human SLC19A1 and eGFP by Flow Cytometry.