HEK293 human embryonic kidney cell line transfected with (A) human Relaxin R2 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human Relaxin R2 Monoclonal Antibody (Catalog # MAB102501) followed by APC-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). Quadrant markers were set based on control antibody staining (Catalog # MAB002). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Relaxin R2 Antibody

Application

Recommended Usage

CyTOF-ready

Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Flow Cytometry

0.25 µg/10⁶ cells
Sample: HEK293 Human Cell Line Transfected with Human Relaxin R2 and eGFP

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Relaxin R2

Relaxin R2 (also known as LGR8) is the G-protein coupled receptor (GPCR) for Relaxin, and may also be a receptor for INSL3. LGR8 can mediate the action of Relaxin through cAMP-dependent pathway distinct from structurally related insulin and insulin-like growth factor family ligand. Distribution of this receptor implicates its role in reproductive, brain, renal, cardiovascular and other functions.

Long Name

Relaxin Receptor 2

Alternate Names

Gpr106, Great, Lgr8, RelaxinR2, RLN2R, Rxfp2

Entrez Gene IDs

122042 (Human); 140498 (Mouse)

Gene Symbol

RXFP2

UniProt

Q8WXD0

Additional Relaxin R2 Products

Product Documents for Human Relaxin R2 Antibody

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Human Relaxin R2 Antibody

For research use only

Citations
Reviews

Calculators
Flow Cytometry

Human Relaxin R2 Antibody

R&D Systems, part of Bio-Techne | Catalog # MAB102501

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

View all Relaxin R2 Antibodies »

Product Specifications

Immunogen

Specificity

Clonality

Host

Isotype

Scientific Data Images for Human Relaxin R2 Antibody

Detection of Relaxin R2 in HEK293 Human Cell Line Transfected with Human Relaxin R2 and eGFP by Flow Cytometry.