Human TGF-beta RII Fluorescein-conjugated Antibody
R&D Systems, part of Bio-Techne | Catalog # FAB2411F
Key Product Details
Species Reactivity
Human
Applications
Flow Cytometry
Label
Fluorescein (Excitation = 488 nm, Emission = 515-545 nm)
Antibody Source
Polyclonal Goat IgG
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human TGF-beta RII
Ile24-Asp159
Accession # P37173.2
Ile24-Asp159
Accession # P37173.2
Specificity
Detects human TGF-beta RII in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse (rm) TGF‑ beta RII and less than 1% cross-reactivity with recombinant human TGF-beta RIII and rmTGF-beta RI is observed.
Clonality
Polyclonal
Host
Goat
Isotype
IgG
Scientific Data Images for Human TGF-beta RII Fluorescein-conjugated Antibody
Detection of TGF‑ beta RII in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2411F, filled histogram) or isotype control antibody (Catalog # IC108F, open histogram). View our protocol for Staining Membrane-associated Proteins.Applications for Human TGF-beta RII Fluorescein-conjugated Antibody
Application
Recommended Usage
Flow Cytometry
10 µL/106 cells
Sample: Human peripheral blood lymphocytes
Sample: Human peripheral blood lymphocytes
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Reviewed Applications
Read 1 review rated 5 using FAB2411F in the following applications:
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: TGF-beta RII
TGF-beta RII is a membrane bound serine/threonine kinase. Upon ligand binding, TGF-beta RII interacts with TGF-beta RI to form the heteromeric signaling complex that transduces TGF-beta signals. A splice variant of the type II receptor, TGF-beta RIIb, containing a 25 amino acid residue insertion near the N-terminus of the mature protein has also been described.
Long Name
Transforming Growth Factor beta Receptor II
Alternate Names
TGF-bRII, TGFbetaRII, TGFBR2
Gene Symbol
TGFBR2
UniProt
Additional TGF-beta RII Products
Product Documents for Human TGF-beta RII Fluorescein-conjugated Antibody
Product Specific Notices for Human TGF-beta RII Fluorescein-conjugated Antibody
For research use only
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