IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14094

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2c Kappa Clone # IGF1R/4667

Format

Azide and BSA Free

Concentration

1 mg/ml

View all IGF-I R/IGF1R Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa550-750) of human IGF-I R/IGF1R protein (exact sequence is proprietary) (Uniprot: P08069)

Localization

Cell membrane

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2c Kappa

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-13948).

Antibody without azide - store at -20 to -80C. Antibody with azide - store at 2 to 8C. Non-hazardous.

Theoretical molecular weight: 130kDa (IGF-1R); 97kDa (IGF-1R); 200kDa (pro-IGF-1R)

Scientific Data Images for IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free

Protein Array: IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free [NBP3-14094]

Protein Array: IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free [NBP3-14094]

Protein Array: IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free [NBP3-14094] - Analysis of Protein Array containing more than 19,000 full-length human proteins using IGF-I R/IGF1R Antibody (IGF1R/4667).

Applications for IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1-2 ug/million cells

Immunocytochemistry/ Immunofluorescence

1-4 ug/ml
Application Notes
In-vitro Neutralization of Biological Activity of IGF-1: Order this antibody without Azide

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: IGF-I R/IGF1R

The IGF1 receptor prefers IGF1 over IGF2 and weakly binds insulin. IGF1 receptor is a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha (130 kD) and two beta (95 kD) subunits. Both the alpha and beta subunits are encoded within a single receptor precursor cDNA. The IGF1 receptor is therefore similar in structure to the insulin receptor. The proreceptor polypeptide is proteolytically cleaved and disulfide-linked to yield the mature heterotetrameric receptor. The IGF1 receptor is highly expressed in all cell types and tissues and is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival

Long Name

Insulin-like Growth Factor I Receptor

Alternate Names

CD221, IGF-1R, IGF-IR, IGF1R, IGFIR

Gene Symbol

IGF1R

Additional IGF-I R/IGF1R Products

Product Documents for IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IGF-I R/IGF1R Antibody (IGF1R/4667) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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