IGF-I R/IGF1R Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-77679

Novus Biologicals, part of Bio-Techne
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NBP1-77679
NBP1-77679SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Primate

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Simple Western, Western Blot

Cited:

Simple Western

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.05 mg/ml

View all IGF-I R/IGF1R Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to a C-terminal portion of the human IGF1 Receptor protein (between residues 1300-1367) [UniProt P08069].

Localization

Membrane.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IGF-I R/IGF1R Antibody - BSA Free

Western Blot: IGF-I R/IGF1R AntibodyBSA Free [NBP1-77679]

Western Blot: IGF-I R/IGF1R AntibodyBSA Free [NBP1-77679]

Western Blot: IGF-I R Antibody [NBP1-77679] - Analysis of IGF-1R in 1. HeLa, 2. Ntera2, 3. A431, 4. HepG2, 5. MCF7, 6. NIH/3T3, 7. SK-BR-3 and 8. COS7
Immunocytochemistry/ Immunofluorescence: IGF-I R/IGF1R Antibody - BSA Free [NBP1-77679]

Immunocytochemistry/ Immunofluorescence: IGF-I R/IGF1R Antibody - BSA Free [NBP1-77679]

Immunocytochemistry/Immunofluorescence: IGF-I R Antibody [NBP1-77679] - IGF-1 R antibody was tested in A431 cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).
Immunohistochemistry-Paraffin: IGF-I R/IGF1R Antibody - BSA Free [NBP1-77679]

Immunohistochemistry-Paraffin: IGF-I R/IGF1R Antibody - BSA Free [NBP1-77679]

Immunohistochemistry-Paraffin: IGF-I R Antibody [NBP1-77679] - IHC analysis of a formalin fixed paraffin embedded tissue section of the human kidney cancer xenograft using 1:200 dilution of IFG-I R antibody (NBP1-77679). The signal was developed using HRP-DAB method which followed counterstaining of the cells with hematoxylin.
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Applications for IGF-I R/IGF1R Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:100

Immunohistochemistry-Paraffin

1:200

Simple Western

1:100

Western Blot

1 ug/ml
Application Notes
This IGFR1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot where a band is seen ~100 kDa.

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 30% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.05 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IGF-I R/IGF1R

Insulin-like growth factor receptor 1 (IGFR1) is a tyrosine kinase receptor that is important in embryonic development. IGFR1 has effects in breast, prostate, gastric and lung cancers, as it can be a player in drug resistance. It also affects the flow of nutrients from mother to placenta to fetus during development. IGFR1 seems to greatly influence the rate of growth of fetuses and newborn babies; when it is not appropriately expressed or regulated, fetal growth restriction occurs. The major activity of IGFR1 is to mediate the signaling of growth signals to effect downstream growth patterns.

Long Name

Insulin-like Growth Factor I Receptor

Alternate Names

CD221, IGF-1R, IGF-IR, IGF1R, IGFIR

Entrez Gene IDs

3480 (Human); 101883 (Mouse)

Gene Symbol

IGF1R

UniProt

P08069

Additional IGF-I R/IGF1R Products

Product Documents for IGF-I R/IGF1R Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IGF-I R/IGF1R Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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