IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14604

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # B-T21

Format

Azide and BSA Free

Concentration

1 mg/ml

View all IL-12/IL-35 p35 Antibodies »

Product Specifications

Immunogen

Recombinant human IL-12/IL-35 p35

Specificity

recognizes both natural and recombinant human IL-12/IL-35 p35

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Scientific Data Images for IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free

ELISA: IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free [NBP3-14604]

ELISA: IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free [NBP3-14604]

ELISA: IL-12/IL-35 p35 Antibody (B-T21) [NBP3-14604] - ELISA quantification of IFNg secretion by PBMC (PHA activated after 72 hours) with IL-12/IL-35 antibody (300 pg/ml) and different concentration of B-T21 or isotype control.

Applications for IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Biological Activity: Inhibits IL-12 induced IFNg synthesis on PHA activated lymphocytes

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL-12/IL-35 p35

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]

Long Name

Interleukin 12 p35

Alternate Names

IL-12A, IL35p35

Gene Symbol

IL12A

Additional IL-12/IL-35 p35 Products

Product Documents for IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL-12/IL-35 p35 Antibody (B-T21) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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