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Inhibin alpha Antibody (4E2) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51660

Novus Biologicals, part of Bio-Techne
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NBP1-51660
NBP1-51660-0.025ml

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 4E2

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Summary for Inhibin alpha Antibody (4E2) - BSA Free

Immunogen

Purified recombinant fragment of human Inhibin alpha expressed in E. Coli.

Reactivity Notes

Human, Mouse. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Inhibin alpha Antibody (4E2) - BSA Free

Western Blot: Inhibin alpha Antibody (4E2)BSA Free [NBP1-51660]

Western Blot: Inhibin alpha Antibody (4E2)BSA Free [NBP1-51660]

Western Blot: Inhibin alpha Antibody (4E2) [NBP1-51660] - Western blot analysis using INHA mouse mAb against mouse spermary (1) tissues lysate.
Immunocytochemistry/ Immunofluorescence: Inhibin alpha Antibody (4E2) - BSA Free [NBP1-51660]

Immunocytochemistry/ Immunofluorescence: Inhibin alpha Antibody (4E2) - BSA Free [NBP1-51660]

Immunocytochemistry/Immunofluorescence: Inhibin alpha Antibody (4E2) [NBP1-51660] - Immunofluorescence analysis of PANC-1 cells using INHA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Applications for Inhibin alpha Antibody (4E2) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Inhibin A

INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

Alternate Names

INHA, Inhibin A

Gene Symbol

INHA

Additional Inhibin A Products

Product Documents for Inhibin alpha Antibody (4E2) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Inhibin alpha Antibody (4E2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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