Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free
Novus Biologicals, part of Bio-Techne | Catalog # NB500-496
![Immunocytochemistry/ Immunofluorescence: Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free [NB500-496]](https://resources.bio-techne.com/images/products/Integrin-alpha-2b-CD41-Antibody-IVA30-Immunocytochemistry-Immunofluorescence-NB500-496-img0001.jpg "Immunocytochemistry/ Immunofluorescence: Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free [NB500-496]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Bovine
Applications
CyTOF-ready, ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2 Clone # IVA30
Format
BSA Free
Concentration
1 mg/ml
Product Summary for Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free
Immunogen
Bovine trombocytes.
Specificity
The antibody IVA30 reacts with CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes; the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2
Scientific Data Images for Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free
Immunocytochemistry/ Immunofluorescence: Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free [NB500-496]
Immunocytochemistry/Immunofluorescence: Integrin alpha 2b/CD41 Antibody (IVA30) [NB500-496] - Immunocytochemistry staining of acetone/methanol fixed bovine peripheral blood (thrombocyte-enriched suspension) using anti-bovine CD41/CD61 (IVA30); secondary antibody conjugated to FITC (green signal at thrombocytes), DNA stained with DAPI (blue signal).![Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free Flow Cytometry: Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free [NB500-496]](https://resources.bio-techne.com/images/products/nb500-496_mouse-monoclonal-integrin-alpha-2b-cd41-antibody-iva30-13120241649372.jpg "Flow Cytometry: Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free [NB500-496]")
Flow Cytometry: Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free [NB500-496]
Separation of bovine CD41/CD61 positive thrombocytes (red-filled) from CD41/CD61 negative leukocytes (black-dashed) in Analysis (surface staining) of bovine peripheral whole blood stained using anti-bovine CD41/CD61 (IVA30) purified antibody (concentration in sample 3 ug/ml, GAM APC).Applications for Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free
Application
Recommended Usage
ELISA
1:2000
Flow Cytometry
1-4 ug/ml
Immunoprecipitation
1:50
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS (pH 7.4)
Format
BSA Free
Preservative
0.9% Sodium Azide
Concentration
1 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C. Do not freeze.
Background: Integrin alpha 2b/CD41
Alternate Names
CD41, GP2B, GPIIb, GTA, HPA3, ITGA2b
Gene Symbol
ITGA2B
Additional Integrin alpha 2b/CD41 Products
Product Documents for Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free
Product Specific Notices for Integrin alpha 2b/CD41 Antibody (IVA30) - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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