Integrin alpha 2b/CD41 Antibody (IVA30) [PE/Cy7]
Novus Biologicals, part of Bio-Techne | Catalog # NB500-496PECY7
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human, Bovine
Applications
Flow Cytometry
Label
PE/Cy7 (Excitation = 488 nm, Emission = 778 nm)
Antibody Source
Monoclonal Mouse IgG2 Clone # IVA30
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Integrin alpha 2b/CD41 Antibody (IVA30) [PE/Cy7]
Immunogen
Bovine trombocytes.
Specificity
The antibody IVA30 reacts with CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes; the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2
Applications for Integrin alpha 2b/CD41 Antibody (IVA30) [PE/Cy7]
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark. Do not freeze.
Background: Integrin alpha 2b/CD41
Alternate Names
CD41, GP2B, GPIIb, GTA, HPA3, ITGA2b
Gene Symbol
ITGA2B
Additional Integrin alpha 2b/CD41 Products
Product Documents for Integrin alpha 2b/CD41 Antibody (IVA30) [PE/Cy7]
Product Specific Notices for Integrin alpha 2b/CD41 Antibody (IVA30) [PE/Cy7]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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