Integrin alpha 2b/CD41 Antibody (PM6/248)
Novus Biologicals, part of Bio-Techne | Catalog # NB100-63779
Clone PM6/248 was used by HLDA to establish CD designation.
![Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) - BSA Free [NB100-63779]](https://resources.bio-techne.com/images/products/Integrin-alpha-2b-CD41-Antibody-PM6-248-Flow-Cytometry-NB100-63779-img0002.jpg "Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) - BSA Free [NB100-63779]")
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Flow Cytometry
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG1 Clone # PM6/248
Concentration
1.0 mg/ml
Product Summary for Integrin alpha 2b/CD41 Antibody (PM6/248)
Immunogen
Human platelet plasma membranes
Reactivity Notes
Reacts with Human. Cross reacts with Baboon, Mink and Mustelid.
Specificity
NB100-63779 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Scientific Data Images for Integrin alpha 2b/CD41 Antibody (PM6/248)
Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) - BSA Free [NB100-63779]
Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) [NB100-63779] - Analysis using the FITC conjugate of NB100-63779. Staining of human peripheral blood platelets.![Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) - BSA Free [NB100-63779]](https://resources.bio-techne.com/images/products/Integrin-alpha-2b-CD41-Antibody-PM6-248-Flow-Cytometry-NB100-63779-img0001.jpg "Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) - BSA Free [NB100-63779]")
Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) - BSA Free [NB100-63779]
Flow Cytometry: Integrin alpha 2b/CD41 Antibody (PM6/248) [NB100-63779] - Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD41: FITC.Applications for Integrin alpha 2b/CD41 Antibody (PM6/248)
Application
Recommended Usage
Flow Cytometry
1:10-1:1000
Application Notes
This antibody did not work for western blot analysis.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Formulation
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: Integrin alpha 2b/CD41
Additional Integrin alpha 2b/CD41 Products
Product Documents for Integrin alpha 2b/CD41 Antibody (PM6/248)
Product Specific Notices for Integrin alpha 2b/CD41 Antibody (PM6/248)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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