Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 405]
Novus Biologicals, part of Bio-Techne | Catalog # NB100-63779V
Clone PM6/248 was used by HLDA to establish CD designation.
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Flow Cytometry
Label
DyLight 405 (Excitation = 400 nm, Emission = 420 nm)
Antibody Source
Monoclonal Mouse IgG1 Clone # PM6/248
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 405]
Immunogen
Human platelet plasma membranes
Reactivity Notes
Reacts with Human. Cross reacts with Baboon, Mink and Mustelid.
Specificity
NB100-63779 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1
Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Applications for Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 405]
Application
Recommended Usage
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Integrin alpha 2b/CD41
Alternate Names
CD41, GP2B, GPIIb, GTA, HPA3, ITGA2b
Gene Symbol
ITGA2B
Additional Integrin alpha 2b/CD41 Products
Product Documents for Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 405]
Product Specific Notices for Integrin alpha 2b/CD41 Antibody (PM6/248) [DyLight 405]
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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