Integrin alpha E/CD103 Antibody (ITGAE/3904R) [Janelia Fluor® 646]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08855JF646
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Janelia Fluor 646
Antibody Source
Recombinant Monoclonal Rabbit IgG Clone # ITGAE/3904R
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant human Integrin alpha E/CD103 protein fragment (aa 775-855) (exact sequence is proprietary) (Uniprot: P38570 )
Localization
Cell surface and cytoplasm
Specificity
This monoclonal antibody recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
Marker
T-Cell Lymphoma & Hairy Cell Leukemia Marker
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG
Applications for Integrin alpha E/CD103 Antibody (ITGAE/3904R) [Janelia Fluor® 646]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Integrin alpha E/CD103
Alternate Names
CD103, HUMINAE, ITGAE
Gene Symbol
ITGAE
Additional Integrin alpha E/CD103 Products
Product Specific Notices for Integrin alpha E/CD103 Antibody (ITGAE/3904R) [Janelia Fluor® 646]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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