Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-27870

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Mouse

Applications

Block/Neutralize, Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # I21/7

Format

Azide and BSA Free

Concentration

0.5 mg/ml

View all Integrin alpha L/CD11a Antibodies »

Product Specifications

Immunogen

Whole BW5147 cells

Specificity

Mouse/Human CD11a

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free [NBP1-27870]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free [NBP1-27870]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - BALB/c mouse splenocytes were stained with Rat Anti-Mouse CD11a-UNLB followed by Mouse Anti-Rat IgG2a-FITC.
Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free [NBP1-27870]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free [NBP1-27870]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - Analysis using the Biotin conjugate of NBP1-27870. Multiple staining of BALB/c splenocytes.
Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free [NBP1-27870]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free [NBP1-27870]

Flow Cytometry: Integrin alpha L/CD11a Antibody (I21/7) [NBP1-27870] - Analysis using the FITC conjugate of NBP1-27870. Double staining of BALB/c spleen cells with rat antimouse CD11a-R-PE and rat anti-mouse CD4+CD8-FITC (Clone GK1.5, Cat. No .NBP1-26693 and Clone 53-6.7, Cat. No. NBP1-26710, respectively).

Applications for Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10 - 1:1000
Application Notes
Although not tested this antibody may be useful for Immunoblotting.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.1M BBS (pH 8.2)

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Integrin alpha L/CD11a

The monoclonal antibody I21/7 reacts with the alpha subunit of mouse CD11a, also known as Leukocyte Function-associated Antigen-1 (LFA-1) and a member of the integrin family of cell adhesion molecules. (1, 2) The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. (2) CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Co-stimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1. (1, 2)

Alternate Names

CD11a, ITGAL, LFA-1 alpha, Ly-15, Ly-21

Gene Symbol

ITGAL

Additional Integrin alpha L/CD11a Products

Product Documents for Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin alpha L/CD11a Antibody (I21/7) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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