Skip to main content

Integrin beta 6 Antibody (CSbeta6) [DyLight 650]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-29800C

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Rat, Primate, Rabbit

Applications

CyTOF-ready, Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Label

DyLight 650 (Excitation = 652 nm, Emission = 672 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # CSbeta6

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

beta 6 knockout mice have been immunized with recombinant secreted human alpaVbeta6.

Reactivity Notes

0

Specificity

Monoclonal antibody MAB2076Z, raised by immunizing beta6 knockout mice with recombinant secreted human alphavbeta6, is useful for flow cytometry and immunoprecipitation in all species tested, including mouse. It also works well for immunohistochemistry of acetone-fixed tissues in several species, including rat, rabbit, monkey, and human. The antibody does not work well for immunohistochemistry of mouse tissue. This antibody does not recognize the aV subunit and does not react with alphaV integrins other than alphavbeta6. Because the antibody is not effective in western Blot, it is unknown whether the epitope recognized by the antibody localizes to the alphavbeta6 heterodimer or to the beta6 subunit only.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Integrin beta 6 Antibody (CSbeta6) [DyLight 650]

Application
Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin beta 6

Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion

Alternate Names

ITGB6

Gene Symbol

ITGB6

Additional Integrin beta 6 Products

Product Documents for Integrin beta 6 Antibody (CSbeta6) [DyLight 650]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin beta 6 Antibody (CSbeta6) [DyLight 650]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Loading...
Loading...
Loading...
Loading...
Loading...
Loading...
×