Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Janelia Fluor 585

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all IRGM Antibodies »

Product Specifications

Immunogen

Synthetic peptide from the N-terminal of Human IRGM

Localization

Golgi Apparatus Membrane|Cell Membrane|Cytoplasmic Vesicle|Phagosome Membrane|Cytoplasmic Vesicle|Autophagosome Membrane|Cell Projection|Phagocytic Cup

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for IRGM Antibody [Janelia Fluor® 585]

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IRGM

Members of the p47 immunity-related GTPase (IRG) family, including IRGM, play an important role in the murine immune system; however, in humans this resistance system is greatly reduced. There is evidence that human IRGM plays a role in autophagy and control of intracellular mycobacteria (Bepken et al., 2005; Singh et al., 2006 [PubMed 16888103]).[supplied by OMIM]

Alternate Names

IFI1, immunity-related GTPase family M protein, immunity-related GTPase family, M, interferon-inducible protein 1, IRGM1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG47, LRG-47, LRG-47-like protein, M1, MGC149263, MGC149264

Gene Symbol

IRGM

Additional IRGM Products

Product Documents for IRGM Antibody [Janelia Fluor® 585]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IRGM Antibody [Janelia Fluor® 585]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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