MALT1 Antibody (SPM578) [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34811F

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP2-32872

Alexa Fluor 350

NBP2-34811AF350

Alexa Fluor 405

NBP2-34811AF405

Alexa Fluor 488

NBP2-34811AF488

Alexa Fluor 532

NBP2-34811AF532

Alexa Fluor 594

NBP2-34811AF594

Alexa Fluor 647

NBP2-34811AF647

Alexa Fluor 700

NBP2-34811AF700

Alexa Fluor 750

NBP2-34811AF750

Biotin

NBP2-34811B

CoraFluor 1

NBP2-34811CL1

DyLight 350

NBP2-34811UV

DyLight 405

NBP2-34811V

DyLight 488

NBP2-34811G

DyLight 550

NBP2-34811R

DyLight 594

NBP2-34811DL594

DyLight 650

NBP2-34811C

DyLight 680

NBP2-34811FR

DyLight 755

NBP2-34811IR

HRP

NBP2-34811H

Janelia Fluor 525

NBP2-34811JF525

Janelia Fluor 549

NBP2-34811JF549

Janelia Fluor 646

NBP2-34811JF646

Janelia Fluor 669

NBP2-34811JF669

Forumulation

Catalog #

Azide and BSA Free

NBP2-34811

IHC-Prediluted

NBP2-44349

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # SPM578

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all MALT1 Antibodies »

Product Specifications

Immunogen

Human MALT1 recombinant fragment (aa701-808) (Uniprot: Q9UDY8)

Localization

Cytoplasmic

Marker

MALT-Lymphoma Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Applications for MALT1 Antibody (SPM578) [FITC]

Application

Recommended Usage

CyTOF-ready

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MALT1

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1), also known as MLT1 or paracaspase 1, is a member of the human paracaspase family and an interacting partner of B-cell lymphoma 10 (Bcl-10) (1). In vitro, In vitro, MALT1 synergizes with BCL10 to enhance nuclear factor B activation (2) and to mediate IB kinase (IKK) activation by facilitating the ubiquitinylation of the NF-B essential modulator (NEMO) (3). MALT1 is found in recurrent chromosomal translocations in non-Hodgkin B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT). One common translocation juxtaposes the MALT1 gene to the IgH promoter region, resulting in up-regulation of Bcl-10 and MALT1 (4). Another common translocation creates a fusion between MALT1 and the inhibitor of apoptosis gene API2 (cIAP2/HIAP1) (5).

Long Name

Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1

Alternate Names

MLT1, Paracaspase

Gene Symbol

MALT1

Additional MALT1 Products

Product Documents for MALT1 Antibody (SPM578) [FITC]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for MALT1 Antibody (SPM578) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews