Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE] [NBP2-72598MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.

Applications for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Mcl-1

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

Long Name

Myeloid Cell Leukemia Sequence 1

Alternate Names

BCL2L3, Mcl1

Gene Symbol

MCL1

Additional Mcl-1 Products

Product Documents for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-72598MFV450

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all Mcl-1 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Scientific Data Images for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE] [NBP2-72598MFV450] -

Applications for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

Flow Cytometry

Immunocytochemistry/ Immunofluorescence

Immunohistochemistry

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Mcl-1

Long Name

Alternate Names

Gene Symbol

Additional Mcl-1 Products

Product Documents for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Mcl-1 Antibody (OTI10F6) [mFluor Violet 450 SE]