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Key Product Details

Species Reactivity

Human

Applications

ELISA, Protein Array, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2c Kappa Clone # ENAH/1988

Concentration

0.2 mg/ml

Product Specifications

Immunogen

Recombinant fragment of human Mena protein (around aa 485-589) (exact sequence is proprietary) (Uniprot: Q8N8S7)

Localization

Cytoplasmic

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2c Kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-79887)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for Mena Antibody (ENAH/1988)

Western Blot: Mena Antibody (ENAH/1988) [NBP2-79752]

Western Blot: Mena Antibody (ENAH/1988) [NBP2-79752]

Western Blot: Mena Antibody (ENAH/1988) [NBP2-79752] - Western Blot Analysis of human HeLa and MCF-7 cell lysate with Mena Antibody (ENAH/1988).
Protein Array: Mena Antibody (ENAH/1988) [NBP2-79752]

Protein Array: Mena Antibody (ENAH/1988) [NBP2-79752]

Protein Array: Mena Antibody (ENAH/1988) [NBP2-79752] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Mena Antibody (ENAH/1988) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5

Applications for Mena Antibody (ENAH/1988)

Application
Recommended Usage

Western Blot

1-2 ug/ml
Application Notes
ELISA: For coating, order Ab without BSA.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Mena

ENAH/MENA belongs to the Ena/vasodilator-stimulated phosphoprotein (VASP) family of proteins which play a role in regulating the actin cytoskeleton for the control of cell shape and movement. The Ena/VASP family of actin binding proteins includes ENAH/MENA which is the human homolog of drosophila Ena (enabled), VASP, and EVL (Ena/vasodilator-stimulated phosphoprotein-like protein). Ena/VASP proteins contain an EVH1 domain, a central proline-rich domain, and a terminal EVH2 domain. ENAH/MENA is not expressed in normal breast but has been detected and associated with breast lesions with a high risk of transformation and primary and metastatic breast cancer.

Alternate Names

ENAH, NDPP1

Gene Symbol

ENAH

UniProt

Additional Mena Products

Product Documents for Mena Antibody (ENAH/1988)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Mena Antibody (ENAH/1988)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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