Mouse Glypican 6 Biotinylated Antibody

Glypican 6 (glypiated proteoglycan 6; also GPC6) is an 85-95 kDa heparan sulfate proteoglycan member of the GPI-linked glypican family of molecules.  It is expressed by postnatal chrondrocytes and embryonic mesenchyme (connective tissue plus smooth muscle cells), and potentially modulates the availability, or signaling, of heparin-binding growth factors.  Mouse Glypican 6 is synthesized as a 532 amino acid (aa) proprecursor that contains a 507 mature region (aa 4-530) and a 25 aa C-terminal prosegment.  There is one potential splice variant that shows a 10 aa insertion after Leu384.  Over aa 4-513, mouse Glypican 6 shares 99% aa identity with both human and rat Glypican 6.