Mouse Melanocortin-3 R/MC3R Antibody
R&D Systems, part of Bio-Techne | Catalog # MAB3737
Conjugate
Catalog #
Key Product Details
Species Reactivity
Validated:
Mouse
Cited:
Human
Applications
Validated:
CyTOF-ready, Flow Cytometry
Cited:
Immunohistochemistry
Label
Unconjugated
Antibody Source
Monoclonal Rat IgG2A Clone # 345404
Product Specifications
Immunogen
Y3 rat myeloid cell line transfeced with mouse Melanocortin 3R/MC3R
Specificity
Detects Melanocortin 3R/MC3R in direct ELISAs and Western blots. Stains mouse Melanocortin 3R/MC3R-transfected cells but not irrelevant transfectants.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for Mouse Melanocortin-3 R/MC3R Antibody
Application
Recommended Usage
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
Flow Cytometry
0.25 µg/106 cells
Sample: Mouse Melanocortin 3R/MC3R transfected HEK293 cells
Sample: Mouse Melanocortin 3R/MC3R transfected HEK293 cells
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Melanocortin-3 R/MC3R
Mouse Melanocortin 3R (MC3R) is a member of the melanocortin receptor family. The 323 amino acid G-protein-coupled 7-transmembrane glycoprotein is expressed in the brain where, along with MC4R, it binds alpha, beta and gamma melanocyte stimulating hormones and is involved in regulating energy balance. MC3R is also expressed by macrophages and plays an anti-inflammatory role in the heart and other tissues. Of the 69 aa that are extracellular, mouse MC3R shares 91% and 78% sequence identity with rat and human MC3R, respectively.
Long Name
Melanocortin 3 Receptor
Alternate Names
MC3R, Melanocortin-3R, Melanocortin3R
Gene Symbol
MC3R
Additional Melanocortin-3 R/MC3R Products
Product Documents for Mouse Melanocortin-3 R/MC3R Antibody
Product Specific Notices for Mouse Melanocortin-3 R/MC3R Antibody
For research use only
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