NCAM-1/CD56 Antibody (CL12732) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18543

Novus Biologicals, part of Bio-Techne
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NBP3-18543-100ul
NBP3-18543-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # CL12732

Format

BSA Free

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all NCAM-1/CD56 Antibodies »

Product Specifications

Immunogen

This antibody was developed using a synthetic peptide derived from P13591, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for NCAM-1/CD56 Antibody (CL12732) - BSA Free

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543]

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543]

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543] - Staining of human heart shows moderate positivity in the intercalated discs in cardiomyocytes.
Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543]

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543]

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543] - Analysis in human cerebral cortex and skeletal muscle tissues using NBP3-18543 antibody. Corresponding NCAM1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543]

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543]

Immunohistochemistry-Paraffin: NCAM-1/CD56 Antibody (CL12732) [NBP3-18543] - Staining of human ovarian cancer (papillary serous cystadenocarcinoma) shows strong membranous positivity in tumor cells.
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Applications for NCAM-1/CD56 Antibody (CL12732) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NCAM-1/CD56

NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig) like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins. NCAM is expressed on most neuroectodermal derived cell lines, tissues and neoplasm such as retinoblastoma, medulloblastoma, astrocytomas and neuroblastoma.

Long Name

Neural Cell Adhesion Molecule

Alternate Names

CD56, NCAM1

Gene Symbol

NCAM1

Additional NCAM-1/CD56 Products

Product Documents for NCAM-1/CD56 Antibody (CL12732) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NCAM-1/CD56 Antibody (CL12732) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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