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Nectin-2/CD112 Antibody (S06-8F3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20070

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20070-100ul
NBP3-20070-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-8F3

Concentration

0.3 mg/ml

Product Summary for Nectin-2/CD112 Antibody (S06-8F3)

Immunogen

A synthetic peptide of human Nectin-2/CD112 (Uniprot # Q92692)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Nectin-2/CD112 Antibody (S06-8F3)

Western Blot: Nectin-2/CD112 Antibody (S06-8F3) [NBP3-20070]

Western Blot: Nectin-2/CD112 Antibody (S06-8F3) [NBP3-20070]

Western Blot: Nectin-2/CD112 Antibody (S06-8F3) [NBP3-20070] - Western blot detection of Nectin-2/CD112 in Hela, A549, HL-60, U251, U87-MG cell lysates using NBP3-20070 (1:1000 diluted). Predicted band size: 58kDa. Observed band size: 70-80kDa.
Immunocytochemistry/ Immunofluorescence: Nectin-2/CD112 Antibody (S06-8F3) [NBP3-20070]

Immunocytochemistry/ Immunofluorescence: Nectin-2/CD112 Antibody (S06-8F3) [NBP3-20070]

Immunocytochemistry/Immunofluorescence: Nectin-2/CD112 Antibody (S06-8F3) [NBP3-20070] - Immunocytochemistry of Nectin-2/CD112 (green) in hela using NBP3-20070 at dilution 1/50, and DAPI (blue)

Applications for Nectin-2/CD112 Antibody (S06-8F3)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/50

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Nectin-2/CD112

Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

Poliovirus Receptor Related 2

Alternate Names

CD112, HVEB, MPH, Nectin2, PRR2, PVRL2

Gene Symbol

NECTIN2

Additional Nectin-2/CD112 Products

Product Documents for Nectin-2/CD112 Antibody (S06-8F3)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Nectin-2/CD112 Antibody (S06-8F3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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