Nectin-2/CD112: Proteins and Enzymes
Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.
8 results for "Nectin-2/CD112 Proteins and Enzymes" in Products
8 results for "Nectin-2/CD112 Proteins and Enzymes" in Products
Nectin-2/CD112: Proteins and Enzymes
Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.
Biotinylated
| Source: | CHO |
| Accession #: | NP_002847.1 |
| Applications: | BA |
Biotinylated
| Source: | HEK293 |
| Accession #: | NP_002847.1 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | NP_002847.1 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | XP_005589607.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | NP_002847 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | P32507 |
| Applications: | Bind |
| Source: | CHO |
| Accession #: | XP_005589607.1 |
| Applications: | BA |
| Applications: | AC |