Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI6E6

Concentration

1 mg/ml

View all OAS2 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 60-335 of human OAS2 (NP_002526) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

78.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for OAS2 Antibody (OTI6E6)

Western Blot: OAS2 Antibody (OTI6E6) [NBP2-46293]

Western Blot: OAS2 Antibody (OTI6E6) [NBP2-46293]

Western Blot: OAS2 Antibody (6E6) [NBP2-46293] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2.
Immunohistochemistry: OAS2 Antibody (OTI6E6) [NBP2-46293]

Immunohistochemistry: OAS2 Antibody (OTI6E6) [NBP2-46293]

Immunohistochemistry: OAS2 Antibody (6E6) [NBP2-46293] - Analysis of Human lymphoma tissue.
Immunohistochemistry: OAS2 Antibody (OTI6E6) [NBP2-46293]

Immunohistochemistry: OAS2 Antibody (OTI6E6) [NBP2-46293]

Immunohistochemistry: OAS2 Antibody (6E6) [NBP2-46293] - Analysis of Human lymph node tissue.

Applications for OAS2 Antibody (OTI6E6)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:150

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: OAS2

OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]

Long Name

2’,5’-Oligoadenylate Synthetase-2

Alternate Names

(2-5')oligo(A) synthase 2, (2'-5')oligo(A) synthetase 2, (2-5')oligo(A) synthetase 2, 2'5' oligoadenylate synthetase 2, 2-5A synthase 2, 2-5A synthetase 2, 2'-5'-oligoadenylate synthase 2, 2'-5'-oligoadenylate synthetase 2 (69-71 kD), 2'-5'-oligoadenylate synthetase 2, 69/71kDa, EC 2.7.7, EC 2.7.7.-, MGC78578, p69 OAS / p71 OAS, p69OAS / p71OAS

Gene Symbol

OAS2

Additional OAS2 Products

Product Documents for OAS2 Antibody (OTI6E6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for OAS2 Antibody (OTI6E6)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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