OTUD5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85044

Novus Biologicals, part of Bio-Techne
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NBP1-85044
NBP1-85044-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (99%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all OTUD5 Antibodies »

Product Summary for OTUD5 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AAASSGLEEWTSRSPRQRSSASSPEHPELHAELGMKPPSPGTVLALAKPPSPCAPGTSSQFSAGADRATSPLVSLYPALECRALIQQMSPSAFGLNDWDDDEILASVLAVSQQEYLD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for OTUD5 Antibody

Immunocytochemistry/ Immunofluorescence: OTUD5 Antibody [NBP1-85044]

Immunocytochemistry/ Immunofluorescence: OTUD5 Antibody [NBP1-85044]

Immunocytochemistry/Immunofluorescence: OTUD5 Antibody [NBP1-85044] - Staining of human cell line A-431 shows localization to cytosol.
Immunohistochemistry-Paraffin: OTUD5 Antibody [NBP1-85044]

Immunohistochemistry-Paraffin: OTUD5 Antibody [NBP1-85044]

Immunohistochemistry-Paraffin: OTUD5 Antibody [NBP1-85044] - Staining of human rectum shows cytoplasmic positivity in glandular cells.

Applications for OTUD5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: OTUD5

OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternate Names

Deubiquitinating enzyme A, DKFZp761A052, DUBAdeubiquinating enzyme A, EC 3.4.19.12, MGC104871, OTU domain containing 5, OTU domain-containing protein 5

Gene Symbol

OTUD5

Additional OTUD5 Products

Product Documents for OTUD5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for OTUD5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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