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OTUD5 Products

OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
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32 results for "OTUD5" in Products

32 results for "OTUD5" in Products

OTUD5 Products

OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
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Applications: IHC, WB
Reactivity: Human, Mouse, Rat, Primate
Applications: IHC, ICC/IF
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, MA, AP
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: AC
Applications: AC
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
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