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p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20793JF525

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Janelia Fluor 525

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # P40/8225R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 525]

Immunogen

Recombinant fragment (around aa1-200) of human p40/deltaNp63 protein (exact sequence is proprietary)

Localization

Nucleus.

Specificity

The p40 (clone P40/8225R) antibody recognizes exclusively delta-Np63 but not TAp63 p40 is a squamous cell carcinoma specific antibody It reacts with the vast majority of cases of squamous cell carcinomas of various origins, but not with adenocarcinomas It is particularly useful in differentiating lung squamous cell carcinoma from lung poorly differentiated adenocarcinoma p40 antibody can also be used as an alternative basal cell/myoepithelial cell marker, which has similar sensitivity and specificity as that of p63 antibody Therefore, p40 antibody may also be used as an alternative immunohistochemical marker for determining prostate adenocarcinoma vs benign prostate glands and for determining breast intraductal carcinoma vs invasive breast ductal carcinoma

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 525]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: p40/deltaNp63

Alternate Names

AIS, amplified in squamous cell carcinoma, B(p51A), B(p51B), Chronic ulcerative stomatitis protein, EEC3, Keratinocyte transcription factor KET, KET, LMS, OFC8, p53CP, SHFM4, TP53CP, TP53L, TP63, TP73L, Transformation-related protein 63, tumor protein p53-competing protein

Gene Symbol

TP63

Additional p40/deltaNp63 Products

Product Documents for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 525]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p40/deltaNp63 Antibody (P40/8225R) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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