PARP Antibody (CL2220) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44461JF525

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP3-44461AF350

Alexa Fluor 405

NBP3-44461AF405

Alexa Fluor 488

NBP3-44461AF488

Alexa Fluor 532

NBP3-44461AF532

Alexa Fluor 594

NBP3-44461AF594

Alexa Fluor 647

NBP3-44461AF647

Alexa Fluor 700

NBP3-44461AF700

Alexa Fluor 750

NBP3-44461AF750

Allophycocyanin

NBP3-44461APC

Biotin

NBP3-44461B

CoraFluor 1

NBP3-44461CL1

DyLight 350

NBP3-44461UV

DyLight 405

NBP3-44461V

DyLight 488

NBP3-44461G

DyLight 550

NBP3-44461R

DyLight 594

NBP3-44461DL594

DyLight 650

NBP3-44461C

DyLight 680

NBP3-44461FR

DyLight 755

NBP3-44461IR

FITC

NBP3-44461F

HRP

NBP3-44461H

Janelia Fluor 549

NBP3-44461JF549

Janelia Fluor 646

NBP3-44461JF646

Janelia Fluor 669

NBP3-44461JF669

mFluor Violet 450 SE

NBP3-44461MFV450

mFluor Violet 500 SE

NBP3-44461MFV500

mFluor Violet 610 SE

NBP3-44461MFV610

PE

NBP3-44461PE

PerCP

NBP3-44461PCP

Forumulation

Catalog #

BSA Free

NBP2-36747

Azide and BSA Free

NBP3-44461

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG₁ Clone # CL2220

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PARP Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P09874, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for PARP Antibody (CL2220) [Janelia Fluor® 525]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PARP

Poly (ADP-ribose) polymerase (PARP) is protein family primarily invloved in DNA repair and programmed cell death. PARP proteins are activated in response to DNA single strand breaks (SSBs). Upon SSB detection, PARP binds the DNA and synthesizes a PAR chain at the damaged site, which then signals the initiation of DNA repair by other enzymes such as XRCC1, DNA ligase III and DNA polymerase beta. After repair, the PAR chains are degraded via PAR glycohydrolase.

PARP is inactivated by caspase cleavage, leading to a programmed cell death pathway.

Long Name

Poly [ADP-ribose] Polymerase

Alternate Names

ADPRT, PARP1, PPOL

Gene Symbol

PARP1

Additional PARP Products

Product Documents for PARP Antibody (CL2220) [Janelia Fluor® 525]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PARP Antibody (CL2220) [Janelia Fluor® 525]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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