PARP Products
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
72 results for "PARP" in Products
72 results for "PARP" in Products
PARP Products
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IP, ICC, KO |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #839120 |
| Applications: | WB, Simple Western, IHC, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD |
![Western Blot: PARP Antibody [NBP2-13732]](https://resources.bio-techne.com/images/products/PARP-Antibody-Western-Blot-NBP2-13732-img0009.jpg "Western Blot: PARP Antibody [NBP2-13732]")
| Reactivity: | Human, Mouse, Rat (Negative) |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #194C1439 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: PARP Antibody (194C1439)CleavedBSA Free [NB100-56599]](https://resources.bio-techne.com/images/products/PARP-Antibody-194C1439-Cleaved-Western-Blot-NB100-56599-img0004.jpg "Western Blot: PARP Antibody (194C1439)CleavedBSA Free [NB100-56599]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL2220 |
| Applications: | IHC, WB, ICC/IF, KD |
![Western Blot: PARP Antibody (CL2220) [NBP2-36747]](https://resources.bio-techne.com/images/products/PARP-Antibody-CL2220-Western-Blot-NBP2-36747-img0014.jpg "Western Blot: PARP Antibody (CL2220) [NBP2-36747]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2G8N7 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: PARP Antibody (2G8N7) [NBP3-15802]](https://resources.bio-techne.com/images/products/PARP-Antibody-2O6H4-Western-Blot-NBP3-15802-img0004.jpg "Western Blot: PARP Antibody (2G8N7) [NBP3-15802]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #8C7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL2209 |
| Applications: | IHC, WB, KD |
![Western Blot: PARP Antibody (CL2209) [NBP2-36748]](https://resources.bio-techne.com/images/products/PARP-Antibody-CL2209-Western-Blot-NBP2-36748-img0007.jpg "Western Blot: PARP Antibody (CL2209) [NBP2-36748]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #7C11 |
| Applications: | IHC, WB, ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #4M9X4 |
| Applications: | WB, IP |
![Western Blot: PARP Antibody (4M9X4)Cleaved [NBP3-15813]](https://resources.bio-techne.com/images/products/PARP-Antibody-4M9X4-Cleaved-Western-Blot-NBP3-15813-img0001.jpg "Western Blot: PARP Antibody (4M9X4)Cleaved [NBP3-15813]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #5H8 |
| Applications: | IHC, ELISA |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
PARP-1 inhibitor
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% (HPLC) |
Potent PARP inhibitor
| Chemical Name: | 4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Purity: | ≥98% (HPLC) |
Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays
| Chemical Name: | β-Nicotinamide-N6-[2-[[6-[fluorescein]-amino]-2-oxohexyl-hexyl]amino]-2-oxoethyl]adenine dinucleotide |
Potent fluorescent PARP inhibitor; cell permeable
| Alternate Names: | AZD2281-BDY FL,Olaparib-BDY FL |
| Chemical Name: | (T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron |
| Purity: | ≥90% (HPLC) |
Biotinylated-NAD+; substrate for ADP-ribosylation
| Chemical Name: | β-Nicotinamide-N6-[2-[[6-[biotinyl]amino]hexyl]amino]-2-oxoethyl]adenine dinucleotide |
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
Biotinylated analog of β-NAD+; commonly used reagent in LSD1 and PARP1 assays
| Alternate Names: | 6-Biotin-17-NAD |
| Chemical Name: | β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide sodium salt |
| Purity: | ≥95% (HPLC) |
PARP inhibitor
| Alternate Names: | CO-338 |
| Chemical Name: | 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2,ef][2]benzazepin-6-one (1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid |
| Purity: | ≥98% (HPLC) |
PARP inhibitor; photoaffinity probe
| Chemical Name: | 3-(3-Butyn-1-yl)-N-[5-cyano-6-[4-[3-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]benzoyl]-1-piperazinyl]-3-pyridinyl]-3H-diazirine-3-propanamide |
| Purity: | ≥95% (HPLC) |
