PAX8 Antibody (CL7834)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21161

Novus Biologicals, part of Bio-Techne
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NBP3-21161-100ul
NBP3-21161-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL7834

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PAX8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a Synthetic Peptide of Q06710. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PAX8 Antibody (CL7834)

Immunohistochemistry-Paraffin: PAX8 Antibody [NBP3-21161] -

Immunohistochemistry-Paraffin: PAX8 Antibody [NBP3-21161] -

Staining of human Fallopian tube shows moderate to strong nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: PAX8 Antibody [NBP3-21161] -

Immunohistochemistry-Paraffin: PAX8 Antibody [NBP3-21161] -

Staining of human renal cancer shows moderate to strong nuclear positivity in tumor cells.
Immunohistochemistry-Paraffin: PAX8 Antibody [NBP3-21161] -

Immunohistochemistry-Paraffin: PAX8 Antibody [NBP3-21161] -

Staining of human thyroid gland shows strong nuclear positivity in glandular cells.
View 3 more images

Applications for PAX8 Antibody (CL7834)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PAX8

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described.

Alternate Names

paired box 8, paired box gene 8, paired box protein Pax-8, paired domain gene 8

Gene Symbol

PAX8

Additional PAX8 Products

Product Documents for PAX8 Antibody (CL7834)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PAX8 Antibody (CL7834)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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