Semaphorin 4D/CD100 Antibody (133-1C6)

Validated:

Cited:

Validated:

Cited:

Unconjugated

Monoclonal Mouse IgM Kappa Clone # 133-1C6

0.2 mg/ml

PHA stimulated human peripheral blood lymphocytes. (Uniprot: Q92854)

Does not react with Equine.

Cell surface

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Monoclonal

Mouse

IgM Kappa

200ug/ml of antibody purified from Bioreactor Concentrate. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-47795)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Protein L or PEG purified

10 mM PBS with 0.05% BSA

0.05% Sodium Azide

0.2 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.