Semaphorin 4D/CD100 Antibody (133-1C6) - Azide and BSA Free

Validated:

Unconjugated

Monoclonal Mouse IgM Kappa Clone # 133-1C6

Azide and BSA Free

1.0 mg/ml

PHA stimulated human peripheral blood lymphocytes. (Uniprot: Q92854)

Does not react with Equine.

Cell surface

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Monoclonal

Mouse

IgM Kappa

1.0 mg/ml of antibody purified from Bioreactor Concentrate. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP2-44362).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Protein L or PEG purified

10 mM PBS

Azide and BSA Free

No Preservative

1.0 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at -20 to -80C. Avoid freeze-thaw cycles.