SLC6A3/DAT1 Antibody (SR1877)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21721

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21721-100ul
NBP3-21721-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1877

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SLC6A3/DAT1 Antibodies »

Product Summary for SLC6A3/DAT1 Antibody (SR1877)

Immunogen

A synthesized peptide derived from human SLC6A3/DAT1 (Uniprot #: Q01959)

Specificity

Detects endogenous levels of total SLC6A3/DAT1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SLC6A3/DAT1 Antibody (SR1877)

Western Blot: SLC6A3/DAT1 Antibody (SR1877) [NBP3-21721] -

Western Blot: SLC6A3/DAT1 Antibody (SR1877) [NBP3-21721] - Western blot analysis using NBP3-21721 in HeLa cell lysate.

Applications for SLC6A3/DAT1 Antibody (SR1877)

Application
Recommended Usage

Flow Cytometry

1:50

Immunoprecipitation

1:50

Western Blot

1:1000-1:5000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC6A3/DAT1

The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).

Long Name

Dopamine Transporter

Alternate Names

DAT1, SLC6A3, VNTR

Gene Symbol

SLC6A3

Additional SLC6A3/DAT1 Products

Product Documents for SLC6A3/DAT1 Antibody (SR1877)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLC6A3/DAT1 Antibody (SR1877)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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