Tau [p Ser202, p Thr205] Antibody (AH36) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18265G

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-18265

Alexa Fluor 350

NBP3-18265AF350

Alexa Fluor 405

NBP3-18265AF405

Alexa Fluor 488

NBP3-18265AF488

Alexa Fluor 532

NBP3-18265AF532

Alexa Fluor 594

NBP3-18265AF594

Alexa Fluor 647

NBP3-18265AF647

Alexa Fluor 700

NBP3-18265AF700

Alexa Fluor 750

NBP3-18265AF750

Biotin

NBP3-18265B

CoraFluor 1

NBP3-18265CL1

DyLight 350

NBP3-18265UV

DyLight 405

NBP3-18265V

DyLight 550

NBP3-18265R

DyLight 594

NBP3-18265DL594

DyLight 650

NBP3-18265C

DyLight 680

NBP3-18265FR

DyLight 755

NBP3-18265IR

FITC

NBP3-18265F

HRP

NBP3-18265H

Janelia Fluor 525

NBP3-18265JF525

Janelia Fluor 549

NBP3-18265JF549

Janelia Fluor 585

NBP3-18265JF585

Janelia Fluor 635

NBP3-18265JF635

Janelia Fluor 646

NBP3-18265JF646

Janelia Fluor 669

NBP3-18265JF669

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse

Applications

Dot Blot, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

DyLight 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Monoclonal Rabbit IgG Clone # AH36

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Tau Antibodies »

Product Specifications

Immunogen

Synthetic peptide of Human Phospho Tau (Ser202/Thr205)

Modification

p Ser202

Localization

Cytoskeleton|Cytosol|Plasma Membrane|Axon|Dendrite

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Applications for Tau [p Ser202, p Thr205] Antibody (AH36) [DyLight 488]

Application

Recommended Usage

Dot Blot

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Tau

Tau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD) (1,2). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Tau's association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404 (3). Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396 (4).

Long Name

Microtubule-Associated Protein Tau

Alternate Names

MAPT, MSTD, MTBT1, Neurofibrillary tangle protein, PPND

Gene Symbol

MAPT

Additional Tau Products

Product Documents for Tau [p Ser202, p Thr205] Antibody (AH36) [DyLight 488]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for Tau [p Ser202, p Thr205] Antibody (AH36) [DyLight 488]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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