ULBP-1 Antibody (13C8) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-26263

Recombinant monoclonal antibody expressed in HEK293F cells
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 13C8

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ULBP-1 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from Human ULBP-1 [UniProt Q9BZM6]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ULBP-1 Antibody (13C8) - BSA Free

ULBP-1 Antibody (13C8)

Western Blot: ULBP-1 Antibody (13C8) [NBP3-26263] -

Western Blot: ULBP-1 Antibody (13C8) [NBP3-26263] - Positive Western Blot detected in: Hela whole cell lysate, MCF-7 whole cell lysate, Raji whole cell lysate, HEK293 whole cell lysate.
All lanes: ULBP-1 Antibody at 1: 1000
Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution.
Predicted band size: 28 kDa
Observed band size: 36-50 kDa

Applications for ULBP-1 Antibody (13C8) - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, and 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -70C. Avoid freeze-thaw cycles.

Background: ULBP-1

Ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signalingpathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands toNKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked theinteraction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system.UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface

Long Name

UL16 Binding Protein-1

Alternate Names

ALCAN-beta, MULT-1, NKG2DL, NKG2DL1, RAET1I, ULBP1

Gene Symbol

ULBP1

Additional ULBP-1 Products

Product Documents for ULBP-1 Antibody (13C8) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ULBP-1 Antibody (13C8) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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