VAMP-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-24599

Novus Biologicals, part of Bio-Techne
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NBP2-24599
NBP2-24599SS
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Key Product Details

Species Reactivity

Validated:

Mouse, Rat

Predicted:

Chimpanzee (100%), Human (100%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all VAMP-2 Antibodies »

Product Summary for VAMP-2 Antibody

Immunogen

A portion of amino acids 1-50 of rat VAMP-2 was used as the immunogen.

Marker

Synaptic Vesicles Marker

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for VAMP-2 Antibody

Western Blot: VAMP-2 Antibody [NBP2-24599]

Western Blot: VAMP-2 Antibody [NBP2-24599]

Western Blot: VAMP-2 Antibody [NBP2-24599] - Analysis of VAMP-2 in mouse embryo brain lysate in the 1) absence and 2) presence of immunizing peptide (1 ug/ml), 3) mouse brain (1 ug/ml) and 4) rat brain lysate (2 ug/ml) using this antibody.

Applications for VAMP-2 Antibody

Application
Recommended Usage

Western Blot

1.0-2.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 ml PBS and 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VAMP-2

Vesicle-associated membrane protein (VAMP), also known as synaptobrevin, is an 18 kDa integral membrane protein localized to the cytoplasmic surface of synaptic vesicle (2). VAMP consists of a proline-rich amino-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a carboxylterminal tail (3). Two VAMP homologs, VAMP1 and VAMP2, are differentially expressed in the nervous system (3). VAMP1 expression is localized to neurons involved in modulating overlapping patterns, whereas VAMP2 is found in neurons ssociated with autonomic, sensory and integrative functions. In non-neuronal tissues, VAMP1 is restricted to pancreas and kidney tubular cells, whereas VAMP2 is predominantly expressed in Langerhans islets and glomerular cells (4). Evidences for VAMP

Long Name

Vesicle-Associated Membrane Protein 2

Alternate Names

SYB2, VAMP2

Gene Symbol

VAMP2

UniProt

P63027

Additional VAMP-2 Products

Product Documents for VAMP-2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for VAMP-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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