Von Hippel Lindau Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-41384

Novus Biologicals, part of Bio-Techne
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NB100-41384
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Predicted:

Canine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all VHL Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RSLVKPENYRRLD corresponding to internal region according to NP_937799.1.

Specificity

This antibody is expected to recognise both reported isoforms (NP_000542.1 and NP_937799.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Von Hippel Lindau Antibody

Western Blot: Von Hippel Lindau Antibody [NB100-41384]

Western Blot: Von Hippel Lindau Antibody [NB100-41384]

Western Blot: Von Hippel Lindau Antibody [NB100-41384] - Staining of Human Ovary lysate (35 ug protein in RIPA buffer). Antibody at 0.01 ug/mL. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NB100-41384]

Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NB100-41384]

Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NB100-41384] - Staining of Human Kidney. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for Von Hippel Lindau Antibody

Application
Recommended Usage

Immunohistochemistry

5 ug/mL

Immunohistochemistry-Paraffin

5 ug/mL

Peptide ELISA

Detection limit 1:128000

Western Blot

0.01 - 0.03 ug/mL

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: VHL

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

Von Hippel-Lindau Tumor Suppressor

Alternate Names

Protein G7, pVHL

Entrez Gene IDs

7428 (Human); 22346 (Mouse); 24874 (Rat)

Gene Symbol

VHL

UniProt

NP_000542.1 (Human)

Additional VHL Products

Product Documents for Von Hippel Lindau Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Von Hippel Lindau Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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