92 results for "VHL" in Products
VHL Products
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1066402 |
| Applications: | WB, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1066409 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #1066408 |
| Applications: | ICC |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C3-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(4-Aminobutanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with PEG linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG3-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-14-amino-2-(tert-butyl)-4-oxo-6,9,12-trioxa-3-azatetradecan-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
High-affinity VHL fluorescent probe for TR-FRET and FP assays
| Chemical Name: | (2S,4R)-1-((S)-2-(tert-Butyl)-21-(5,5-difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-4,19-dioxo-6,9,12,15-tetraoxa-3,18-diazahenicosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | (2S,4R)-N-(2-(4-Aminobutoxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Chemical Name: | (2S,4R)-N-(2-((6-Aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-1-((S)-2-(1-fluorocyclopropane-1-carboxamido)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with PEG linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG5-COOH |
| Chemical Name: | (S)-21-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-22,22-dimethyl-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanoic acid |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C7-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(8-Aminooctanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C4-COOH |
| Chemical Name: | 6-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-6-oxohexanoic acid |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C8-COOH |
| Chemical Name: | 10-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecanoic acid |
| Purity: | ≥95% (HPLC) |
Inhibitor of VHL; blocks interaction of VHL and HIF-α
| Chemical Name: | (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C2-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C2-COOH |
| Chemical Name: | 4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid |
| Purity: | ≥95% (HPLC) |
VHL ligand, carboxylic acid functionalized at the benzylic position
| Chemical Name: | (S)-3-[[[(2S,4R)-1-[(S)-2-(1-Fluorocyclopropan-1-ylcarbonylamino)-3,3-dimethylbutanoyl]-4-hydroxypyrrolidin-2-yl]carbonyl]amino]-3-[4-(4-methylthiazol-5-yl)phenyl]propanoic acid |
| Purity: | ≥98% (HPLC) |
Functionalized VHL ligand for PROTACs
| Chemical Name: | (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C5-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(6-Aminohexanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with PEG linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG2-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(2-(2-(2-Aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥95% (HPLC) |
VHL ligand with PEG linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG2-COOH |
| Chemical Name: | 3-(2-(3-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)ethoxy)propanoic acid |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C3-COOH |
| Chemical Name: | 5-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentanoic acid |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-C9-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-(10-Aminodecanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
VHL ligand with PEG linker and terminal acid for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-PEG1-COOH |
| Chemical Name: | 3-(3-(((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)propanoic acid |
| Purity: | ≥95% (HPLC) |
VHL ligand with alkyl linker and terminal amine for onward chemistry
| Alternate Names: | (S,R,S)-AHPC-phenol-C6-NH2 |
| Chemical Name: | (2S,4R)-1-((S)-2-Acetamido-3,3-dimethylbutanoyl)-N-(2-((6-aminohexyl)oxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxypyrrolidine-2-carboxamide dihydrochloride |
| Purity: | ≥95% (HPLC) |
