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Von Hippel Lindau Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25225

Novus Biologicals, part of Bio-Techne
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NBP3-25225

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Von Hippel Lindau Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Von Hippel Lindau using the following amino acid sequence: RRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Von Hippel Lindau Antibody

Von Hippel Lindau Antibody Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NBP3-25225]

Immunohistochemistry-Paraffin: Von Hippel Lindau Antibody [NBP3-25225]

Staining of human tonsil shows strong cytoplasmic positivity in squamous epithelial cells, germinal center cells and non-germinal center cells.

Applications for Von Hippel Lindau Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VHL

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Long Name

Von Hippel-Lindau Tumor Suppressor

Alternate Names

Protein G7, pVHL

Gene Symbol

VHL

Additional VHL Products

Product Documents for Von Hippel Lindau Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Von Hippel Lindau Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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