ZFYVE27 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83512

Novus Biologicals, part of Bio-Techne
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NBP1-83512
NBP1-83512-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ZFYVE27 Antibodies »

Product Summary for ZFYVE27 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ZFYVE27 Antibody

Western Blot: ZFYVE27 Antibody [NBP1-83512]

Western Blot: ZFYVE27 Antibody [NBP1-83512]

Western Blot: ZFYVE27 Antibody [NBP1-83512] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue
Immunohistochemistry-Paraffin: ZFYVE27 Antibody [NBP1-83512]

Immunohistochemistry-Paraffin: ZFYVE27 Antibody [NBP1-83512]

Immunohistochemistry-Paraffin: ZFYVE27 Antibody [NBP1-83512] - Staining of human kidney shows strong cytoplasmic granular positivity in cells in tubules.
Immunohistochemistry-Paraffin: ZFYVE27 Antibody [NBP1-83512]

Immunohistochemistry-Paraffin: ZFYVE27 Antibody [NBP1-83512]

Immunohistochemistry-Paraffin: ZFYVE27 Antibody [NBP1-83512] - Staining of human colon shows strong cytoplasmic granular positivity in glandular cells.
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Applications for ZFYVE27 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ZFYVE27

ZFYVE27 is a gene that codes for a protein with eight isoforms, with lengths of 411, 404, 416, 285, 318, 286, 311, and 372 amino acids and weights of approximately 46, 45, 46, 31, 35, 32, 35, and 41 kDa respectively. ZFYVE27 is an upstream inhibitor of RAB11, which regulates directional protein transport to the forming neurites, meaning it is involved in nerve growth factor-induced neurite formation. Current research is being done on several diseases and disorders related to this gene including paraplegia, spasticity, cholangiocarcinoma, and Alzheimer's disease. ZFYVE27 has also been shown to have interactions with VAPA, VAPB, FKBP8, RAB11A, and CCT3.

Alternate Names

FLJ32919, PROTRUDIN, RP11-459F3.2, SPG33, zinc finger FYVE domain-containing protein 27, zinc finger, FYVE domain containing 27

Gene Symbol

ZFYVE27

Additional ZFYVE27 Products

Product Documents for ZFYVE27 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ZFYVE27 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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