Recombinant Human Histone Deacetylase 8/HDAC8 His Protein

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-78828

Novus Biologicals, part of Bio-Techne
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Key Product Details

Source

Baculovirus

Tag

His

Conjugate

Unconjugated

Applications

SDS-PAGE

View all Histone Deacetylase 8/HDAC8 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-377 of Human Histone Deacetylase 8/HDAC8

Source: Baculovirus

Amino Acid Sequence: MEEPEEPADS GQSLVPVYIY SPEYVSMCDS LAKIPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDDDH PDSIEYGLGY DCPATEGIFD YAAAIGGATI TAAQCLIDGM CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFE RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDVSDVGLG KGRYYSVNVP IQDGIQDEKY YQICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY ILQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVVHHH HHH

Purity

>80%, by SDS-PAGE

Endotoxin Level

< 1 EU per 1ug of protein (determined by LAL method)

Predicted Molecular Mass

42.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human Histone Deacetylase 8/HDAC8 His Protein

SDS-PAGE: Recombinant Human Histone Deacetylase 8/HDAC8 His Protein [NBP1-78828]

SDS-PAGE: Recombinant Human Histone Deacetylase 8/HDAC8 His Protein [NBP1-78828]

SDS-Page: Recombinant Human Histone Deacetylase 8/HDAC8 Protein [NBP1-78828]

Formulation, Preparation and Storage

NBP1-78828
Formulation 20 mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1 M NaCl, 1 mM DTT
Preservative No Preservative
Concentration 0.25 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Histone Deacetylase 8/HDAC8

HDAC8, also known as histone deacetylase 8, belongs to class 1 of the histone deacetylase/acuc/apha family. This protein is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Recombinant human HDAC8 protein, fused to His-tag at C-terminus, was expressed in Sf9 insect cell and purified by using conventional chromatography.

Alternate Names

HDAC8, HDACL1, RPD3

Gene Symbol

HDAC8

Additional Histone Deacetylase 8/HDAC8 Products

Product Documents for Recombinant Human Histone Deacetylase 8/HDAC8 His Protein

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Recombinant Human Histone Deacetylase 8/HDAC8 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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