Histone Deacetylase 8/HDAC8 Products
Human Histone Deacetylase 8 (HDAC8) is a member of the class I histone Deacetylases (HDACs). Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation. Like other class I and II HDAC members, the activity of HDAC8 is sensitive to HDAC inhibitor trichostatin A.
Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A
50 results for "Histone Deacetylase 8/HDAC8" in Products
50 results for "Histone Deacetylase 8/HDAC8" in Products
Histone Deacetylase 8/HDAC8 Products
Human Histone Deacetylase 8 (HDAC8) is a member of the class I histone Deacetylases (HDACs). Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation. Like other class I and II HDAC members, the activity of HDAC8 is sensitive to HDAC inhibitor trichostatin A.
Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1O2Y5 |
| Applications: | IHC, WB, ICC/IF, IP, KO |
![Western Blot: Histone Deacetylase 8/HDAC8 Antibody (1O2Y5) [NBP3-16713]](https://resources.bio-techne.com/images/products/Histone-Deacetylase-8-HDAC8-Antibody-1O2Y5-Western-Blot-NBP3-16713-img0007.jpg "Western Blot: Histone Deacetylase 8/HDAC8 Antibody (1O2Y5) [NBP3-16713]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human Histone Deacetylase 8/HDAC8 His Protein [NBP1-78828]](https://resources.bio-techne.com/images/products/Histone-Deacetylase-8-HDAC8-Protein-SDS-Page-NBP1-78828-img0001.jpg "SDS-PAGE: Recombinant Human Histone Deacetylase 8/HDAC8 His Protein [NBP1-78828]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KO |
![Western Blot: Histone Deacetylase 8/HDAC8 AntibodyBSA Free [NBP3-03473]](https://resources.bio-techne.com/images/products/Histone-Deacetylase-8-HDAC8-Antibody-Western-Blot-NBP3-03473-img0005.jpg "Western Blot: Histone Deacetylase 8/HDAC8 AntibodyBSA Free [NBP3-03473]")
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #2F4 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: Histone Deacetylase 8/HDAC8 Antibody (2F4) [H00055869-M01]](https://resources.bio-techne.com/images/products/Histone-Deacetylase-8-HDAC8-Antibody-2F4-Western-Blot-H00055869-M01-img0010.jpg "Western Blot: Histone Deacetylase 8/HDAC8 Antibody (2F4) [H00055869-M01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Histone Deacetylase 8/HDAC8 Antibody [NBP2-98969]](https://resources.bio-techne.com/images/products/Histone-Deacetylase-8-HDAC8-Antibody-Western-Blot-NBP2-98969-img0002.jpg "Western Blot: Histone Deacetylase 8/HDAC8 Antibody [NBP2-98969]")
| Applications: | WB |
![Western Blot: Histone Deacetylase 8/HDAC8 Overexpression Lysate [NBL1-11485]](https://resources.bio-techne.com/images/products/HDAC8-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11485-img0002.jpg "Western Blot: Histone Deacetylase 8/HDAC8 Overexpression Lysate [NBL1-11485]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: Histone Deacetylase 8/HDAC8 Antibody [NBP2-14085]](https://resources.bio-techne.com/images/products/Histone-Deacetylase-8-HDAC8-Antibody-Immunohistochemistry-Paraffin-NBP2-14085-img0011.jpg "Immunohistochemistry-Paraffin: Histone Deacetylase 8/HDAC8 Antibody [NBP2-14085]")
| Applications: | PAGE |
![SDS-PAGE: Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein [NBP2-59518]](https://resources.bio-techne.com/images/products/Recombinant-Human--Mouse-Histone-Deacetylase-8-HDAC8-Protein-SDS-Page-NBP2-59518-img0002.jpg "SDS-PAGE: Recombinant Mouse Histone Deacetylase 8/HDAC8 His Protein [NBP2-59518]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Applications: | NULL |
| Source: | Sf 21 (baculovirus) |
| Accession #: | AAH50433 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% |
Histone deacetylase inhibitor
| Chemical Name: | Sodium 2-propylpentanoate |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥99% (HPLC) |
Dual histone deacetylase (HDAC) 6/8 inhibitor
| Chemical Name: | N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective HDAC8 inhibitor
| Chemical Name: | N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide |
| Purity: | ≥98% (HPLC) |
HDAC (Class I) inhibitor
| Chemical Name: | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate |
| Purity: | ≥99% |
Potent class I and IIb HDAC inhibitor
| Chemical Name: | 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide |
| Purity: | ≥98% (HPLC) |
Potent and selective class IIa HDAC inhibitor; brain penetrant
| Chemical Name: | 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |