AH 7614

Tocris Bioscience, part of Bio-Techne | Catalog # 5256

COA / SDS

Selective FFA4 (GPR120) antagonist

Key Product Details

Chemical Name:	4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide
Purity:	≥98%

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Technical Data
Citations

Biological Activity for AH 7614

AH 7614 is a selective free fatty acid receptor 4 (FFA4/GPR120) antagonist (pIC₅₀ values are 7.1 and <4.6 for human FFA4 and FFA1 receptors respectively). Inhibits linoleic acid and GSK 137647A-induced intracellular calcium accumulation in U2OS osteosarcoma cells expressing the FFA4 receptor.

Technical Data for AH 7614

Formula	C₂₀H₁₇NO₃S
Storage	Store at +4°C
Purity	≥98%
CAS Number	6326-06-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for AH 7614

Solubility

Soluble Soluble to 100 mM in DMSO

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References for AH 7614

References are publications that support the biological activity of the product.

H Sato, Y Taketomi, Y Miki, R Murase, K Yamamoto, M Murakami Secreted Phospholipase PLA2G2D Contributes to Metabolic Health by Mobilizing ?3 Polyunsaturated Fatty Acids in WAT Cell Rep, 2020;31(5):107579. 2020 PMID: 32375030
Sparks et al. Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg.Med.Chem.Lett., 2014;24:3100 PMID: 24881566

AH 7614

Tocris Bioscience, part of Bio-Techne | Catalog # 5256

Key Product Details

Biological Activity for AH 7614

Technical Data for AH 7614

Solubility for AH 7614

Dilution Calculator

Reconstitution Calculator

References for AH 7614

Product Documents for AH 7614

COA

Certificate of Analysis

SDS

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